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T-bet in Tfh cells: Now you see me, now you don’t
In this issue, Fang et al. (https://doi.org/10.1084/jem.20180927) report on a subset of T follicular helper (Tfh) cells that transiently expresses T-bet yet continues to produce IFN-γ at late stages of GC reactions following immunization. They find other genes uniquely expressed in this IFN-γ–produc...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219747/ https://www.ncbi.nlm.nih.gov/pubmed/30337467 http://dx.doi.org/10.1084/jem.20181878 |
| _version_ | 1783368711408713728 |
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| author | Kaech, Susan M. |
| author_facet | Kaech, Susan M. |
| author_sort | Kaech, Susan M. |
| collection | PubMed |
| description | In this issue, Fang et al. (https://doi.org/10.1084/jem.20180927) report on a subset of T follicular helper (Tfh) cells that transiently expresses T-bet yet continues to produce IFN-γ at late stages of GC reactions following immunization. They find other genes uniquely expressed in this IFN-γ–producing Tfh subset, such as NKG2D, that can be used to better distinguish these functionally distinct Tfh cells. |
| format | Online Article Text |
| id | pubmed-6219747 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| publisher | Rockefeller University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-62197472019-05-05 T-bet in Tfh cells: Now you see me, now you don’t Kaech, Susan M. J Exp Med News In this issue, Fang et al. (https://doi.org/10.1084/jem.20180927) report on a subset of T follicular helper (Tfh) cells that transiently expresses T-bet yet continues to produce IFN-γ at late stages of GC reactions following immunization. They find other genes uniquely expressed in this IFN-γ–producing Tfh subset, such as NKG2D, that can be used to better distinguish these functionally distinct Tfh cells. Rockefeller University Press 2018-11-05 /pmc/articles/PMC6219747/ /pubmed/30337467 http://dx.doi.org/10.1084/jem.20181878 Text en © 2018 Kaech http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
| spellingShingle | News Kaech, Susan M. T-bet in Tfh cells: Now you see me, now you don’t |
| title | T-bet in Tfh cells: Now you see me, now you don’t |
| title_full | T-bet in Tfh cells: Now you see me, now you don’t |
| title_fullStr | T-bet in Tfh cells: Now you see me, now you don’t |
| title_full_unstemmed | T-bet in Tfh cells: Now you see me, now you don’t |
| title_short | T-bet in Tfh cells: Now you see me, now you don’t |
| title_sort | t-bet in tfh cells: now you see me, now you don’t |
| topic | News |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219747/ https://www.ncbi.nlm.nih.gov/pubmed/30337467 http://dx.doi.org/10.1084/jem.20181878 |
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