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Genotype to phenotype: Diet-by-mitochondrial DNA haplotype interactions drive metabolic flexibility and organismal fitness
Diet may be modified seasonally or by biogeographic, demographic or cultural shifts. It can differentially influence mitochondrial bioenergetics, retrograde signalling to the nuclear genome, and anterograde signalling to mitochondria. All these interactions have the potential to alter the frequencie...
Autores principales: | Aw, Wen C., Towarnicki, Samuel G., Melvin, Richard G., Youngson, Neil A., Garvin, Michael R., Hu, Yifang, Nielsen, Shaun, Thomas, Torsten, Pickford, Russell, Bustamante, Sonia, Vila-Sanjurjo, Antón, Smyth, Gordon K., Ballard, J. William O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219761/ https://www.ncbi.nlm.nih.gov/pubmed/30399141 http://dx.doi.org/10.1371/journal.pgen.1007735 |
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