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Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition

Accurate predictions of T-cell epitopes would be useful for designing vaccines, immunotherapies for cancer and autoimmune diseases, and improved protein therapies. The humoral immune response involves uptake of antigens by antigen presenting cells (APCs), APC processing and presentation of peptides...

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Detalles Bibliográficos
Autores principales:	Schneidman-Duhovny, Dina, Khuri, Natalia, Dong, Guang Qiang, Winter, Michael B., Shifrut, Eric, Friedman, Nir, Craik, Charles S., Pratt, Kathleen P., Paz, Pedro, Aswad, Fred, Sali, Andrej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219782/ https://www.ncbi.nlm.nih.gov/pubmed/30399156 http://dx.doi.org/10.1371/journal.pone.0206654

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