Metformin reveals a mitochondrial copper addiction of mesenchymal cancer cells

The clinically approved drug metformin has been shown to selectively kill persister cancer cells through mechanisms that are not fully understood. To provide further mechanistic insights, we developed a drug surrogate that phenocopies metformin and can be labeled in situ by means of click chemistry....

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Detalles Bibliográficos
Autores principales: Müller, Sebastian, Versini, Antoine, Sindikubwabo, Fabien, Belthier, Guillaume, Niyomchon, Supaporn, Pannequin, Julie, Grimaud, Laurence, Cañeque, Tatiana, Rodriguez, Raphaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219783/
https://www.ncbi.nlm.nih.gov/pubmed/30399175
http://dx.doi.org/10.1371/journal.pone.0206764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219783/
https://www.ncbi.nlm.nih.gov/pubmed/30399175
http://dx.doi.org/10.1371/journal.pone.0206764

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