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Hydroxychloroquine partially prevents endothelial dysfunction induced by anti-beta-2-GPI antibodies in an in vivo mouse model of antiphospholipid syndrome

BACKGROUND: Antiphospholipid syndrome is associated with endothelial dysfunction, which leads to thrombosis and early atheroma. Given that hydroxychloroquine has anti-thrombotic properties in lupus, we hypothesized that it could reduce endothelial dysfunction in an animal model of antiphospholipid s...

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Detalles Bibliográficos
Autores principales:	Urbanski, Geoffrey, Caillon, Antoine, Poli, Caroline, Kauffenstein, Gilles, Begorre, Marc-Antoine, Loufrani, Laurent, Henrion, Daniel, Belizna, Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219787/ https://www.ncbi.nlm.nih.gov/pubmed/30399161 http://dx.doi.org/10.1371/journal.pone.0206814

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