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Extracellular microvesicle microRNAs as predictive biomarkers for targeted therapy in metastastic cutaneous malignant melanoma

BACKGROUND: Mitogen activated-protein kinase pathway inhibitors (MAPKis) improve treatment outcome in patients with disseminated BRAFV600 mutant cutaneous malignant melanoma (CMM) but responses are of limited duration due to emerging resistance. Although extensive research in mechanisms of resistanc...

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Detalles Bibliográficos
Autores principales:	Svedman, Fernanda Costa, Lohcharoenkal, Warangkana, Bottai, Matteo, Brage, Suzanne Egyhazi, Sonkoly, Enikö, Hansson, Johan, Pivarcsi, Andor, Eriksson, Hanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219796/ https://www.ncbi.nlm.nih.gov/pubmed/30399176 http://dx.doi.org/10.1371/journal.pone.0206942

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