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Phencyclidine dose optimisation for induction of spatial learning and memory deficits related to schizophrenia in C57BL/6 mice

Phencyclidine (PCP) has been used to model cognitive deficits related to schizophrenia in rats and mice. However, the model in mice is not consistent in terms of the PCP effective dose reported. Furthermore, most of the previous studies in mice excluded the presence of drug washout period in the reg...

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Detalles Bibliográficos
Autores principales: Zain, Mohd Aizat, Rouhollahi, Elham, Pandy, Vijayapandi, Mani, Vasudevan, Majeed, Abu Bakar Abdul, Wong, Won Fen, Mohamed, Zahurin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219884/
https://www.ncbi.nlm.nih.gov/pubmed/29731492
http://dx.doi.org/10.1538/expanim.18-0006