Cargando…

Longitudinal echocardiographic and clinical follow-up of patients undergoing mitral valve surgery without concomitant tricuspid valve repair

BACKGROUND: In patients with mild to moderate functional tricuspid regurgitation (TR) and absence of right ventricular dysfunction or tricuspid annulus (TA) dilatation, there is currently no indication for concomitant tricuspid valve (TV) repair during elective mitral valve (MV) surgery. However, lo...

Descripción completa

Detalles Bibliográficos
Autores principales: Jansen, R., van Klarenbosch, B. R., Cramer, M. J., Meijer, R. C. A., Westendorp, P. H. M., Meijburg, H. W. J., Bucx, J. J. J., Chamuleau, S. A. J., Kluin, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bohn Stafleu van Loghum 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220025/
https://www.ncbi.nlm.nih.gov/pubmed/30276525
http://dx.doi.org/10.1007/s12471-018-1159-4
_version_ 1783368744525889536
author Jansen, R.
van Klarenbosch, B. R.
Cramer, M. J.
Meijer, R. C. A.
Westendorp, P. H. M.
Meijburg, H. W. J.
Bucx, J. J. J.
Chamuleau, S. A. J.
Kluin, J.
author_facet Jansen, R.
van Klarenbosch, B. R.
Cramer, M. J.
Meijer, R. C. A.
Westendorp, P. H. M.
Meijburg, H. W. J.
Bucx, J. J. J.
Chamuleau, S. A. J.
Kluin, J.
author_sort Jansen, R.
collection PubMed
description BACKGROUND: In patients with mild to moderate functional tricuspid regurgitation (TR) and absence of right ventricular dysfunction or tricuspid annulus (TA) dilatation, there is currently no indication for concomitant tricuspid valve (TV) repair during elective mitral valve (MV) surgery. However, long-term results are conflicting. Here, we sought to determine the clinical outcome of this cohort, the rate of TR progression after MV surgery and the role of MV aetiology. METHODS: Patients for elective MV surgery without concomitant TV repair were retrospectively analysed with longitudinal echocardiographic and clinical follow-up, focusing on TR progression and MV aetiology. Linear regression analysis was performed for change in TR at follow-up, using pre-determined variables and confounders. RESULTS: In total 204 patients without TV repair were analysed. Development of more than moderate TR after a median of 3.1 [1.6–4.6] years was rarely seen: only in 2 out of 161 patients (1.2%) with known TR grade at follow-up. Overall, median preoperative and late postoperative TR grade were equal (p = 0.116). Subanalysis showed no significant difference in MV aetiology subgroups. Preoperative TR grade and male gender were inversely correlated to change in TR. Mortality was not influenced by the 1‑year postoperative TR severity. CONCLUSION: Our data showed that in a study population of patients with mild to moderate TR undergoing MV surgery without concomitant TV repair, significant late TR was rarely seen. Based on our study, it is safe to waive concomitant TV repair in this specific patient cohort. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s12471-018-1159-4) contains supplementary material, which is available to authorized users.
format Online
Article
Text
id pubmed-6220025
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Bohn Stafleu van Loghum
record_format MEDLINE/PubMed
spelling pubmed-62200252018-11-16 Longitudinal echocardiographic and clinical follow-up of patients undergoing mitral valve surgery without concomitant tricuspid valve repair Jansen, R. van Klarenbosch, B. R. Cramer, M. J. Meijer, R. C. A. Westendorp, P. H. M. Meijburg, H. W. J. Bucx, J. J. J. Chamuleau, S. A. J. Kluin, J. Neth Heart J Original Article BACKGROUND: In patients with mild to moderate functional tricuspid regurgitation (TR) and absence of right ventricular dysfunction or tricuspid annulus (TA) dilatation, there is currently no indication for concomitant tricuspid valve (TV) repair during elective mitral valve (MV) surgery. However, long-term results are conflicting. Here, we sought to determine the clinical outcome of this cohort, the rate of TR progression after MV surgery and the role of MV aetiology. METHODS: Patients for elective MV surgery without concomitant TV repair were retrospectively analysed with longitudinal echocardiographic and clinical follow-up, focusing on TR progression and MV aetiology. Linear regression analysis was performed for change in TR at follow-up, using pre-determined variables and confounders. RESULTS: In total 204 patients without TV repair were analysed. Development of more than moderate TR after a median of 3.1 [1.6–4.6] years was rarely seen: only in 2 out of 161 patients (1.2%) with known TR grade at follow-up. Overall, median preoperative and late postoperative TR grade were equal (p = 0.116). Subanalysis showed no significant difference in MV aetiology subgroups. Preoperative TR grade and male gender were inversely correlated to change in TR. Mortality was not influenced by the 1‑year postoperative TR severity. CONCLUSION: Our data showed that in a study population of patients with mild to moderate TR undergoing MV surgery without concomitant TV repair, significant late TR was rarely seen. Based on our study, it is safe to waive concomitant TV repair in this specific patient cohort. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s12471-018-1159-4) contains supplementary material, which is available to authorized users. Bohn Stafleu van Loghum 2018-10-01 2018-11 /pmc/articles/PMC6220025/ /pubmed/30276525 http://dx.doi.org/10.1007/s12471-018-1159-4 Text en © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Jansen, R.
van Klarenbosch, B. R.
Cramer, M. J.
Meijer, R. C. A.
Westendorp, P. H. M.
Meijburg, H. W. J.
Bucx, J. J. J.
Chamuleau, S. A. J.
Kluin, J.
Longitudinal echocardiographic and clinical follow-up of patients undergoing mitral valve surgery without concomitant tricuspid valve repair
title Longitudinal echocardiographic and clinical follow-up of patients undergoing mitral valve surgery without concomitant tricuspid valve repair
title_full Longitudinal echocardiographic and clinical follow-up of patients undergoing mitral valve surgery without concomitant tricuspid valve repair
title_fullStr Longitudinal echocardiographic and clinical follow-up of patients undergoing mitral valve surgery without concomitant tricuspid valve repair
title_full_unstemmed Longitudinal echocardiographic and clinical follow-up of patients undergoing mitral valve surgery without concomitant tricuspid valve repair
title_short Longitudinal echocardiographic and clinical follow-up of patients undergoing mitral valve surgery without concomitant tricuspid valve repair
title_sort longitudinal echocardiographic and clinical follow-up of patients undergoing mitral valve surgery without concomitant tricuspid valve repair
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220025/
https://www.ncbi.nlm.nih.gov/pubmed/30276525
http://dx.doi.org/10.1007/s12471-018-1159-4
work_keys_str_mv AT jansenr longitudinalechocardiographicandclinicalfollowupofpatientsundergoingmitralvalvesurgerywithoutconcomitanttricuspidvalverepair
AT vanklarenboschbr longitudinalechocardiographicandclinicalfollowupofpatientsundergoingmitralvalvesurgerywithoutconcomitanttricuspidvalverepair
AT cramermj longitudinalechocardiographicandclinicalfollowupofpatientsundergoingmitralvalvesurgerywithoutconcomitanttricuspidvalverepair
AT meijerrca longitudinalechocardiographicandclinicalfollowupofpatientsundergoingmitralvalvesurgerywithoutconcomitanttricuspidvalverepair
AT westendorpphm longitudinalechocardiographicandclinicalfollowupofpatientsundergoingmitralvalvesurgerywithoutconcomitanttricuspidvalverepair
AT meijburghwj longitudinalechocardiographicandclinicalfollowupofpatientsundergoingmitralvalvesurgerywithoutconcomitanttricuspidvalverepair
AT bucxjjj longitudinalechocardiographicandclinicalfollowupofpatientsundergoingmitralvalvesurgerywithoutconcomitanttricuspidvalverepair
AT chamuleausaj longitudinalechocardiographicandclinicalfollowupofpatientsundergoingmitralvalvesurgerywithoutconcomitanttricuspidvalverepair
AT kluinj longitudinalechocardiographicandclinicalfollowupofpatientsundergoingmitralvalvesurgerywithoutconcomitanttricuspidvalverepair