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Polymicrobial Sepsis Chronic Immunoparalysis Is Defined by Diminished Ag-Specific T Cell-Dependent B Cell Responses

Immunosuppression is one hallmark of sepsis, decreasing the host response to the primary septic pathogens and/or secondary nosocomial infections. CD4 T cells and B cells are among the array of immune cells that experience reductions in number and function during sepsis. “Help” from follicular helper...

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Detalles Bibliográficos
Autores principales:	Sjaastad, Frances V., Condotta, Stephanie A., Kotov, Jessica A., Pape, Kathryn A., Dail, Cody, Danahy, Derek B., Kucaba, Tamara A., Tygrett, Lorraine T., Murphy, Katherine A., Cabrera-Perez, Javier, Waldschmidt, Thomas J., Badovinac, Vladimir P., Griffith, Thomas S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220049/ https://www.ncbi.nlm.nih.gov/pubmed/30429857 http://dx.doi.org/10.3389/fimmu.2018.02532

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