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Verapamil Ameliorates Hepatic Metaflammation by Inhibiting Thioredoxin-Interacting Protein/NLRP3 Pathways

Activation of thioredoxin-interacting protein (TXNIP)/nod-like receptor protein 3 (NLRP3) inflammasome plays a critical role in pathogenesis of non-alcoholic fatty liver disease. This study investigated the protective effects of verapamil on hepatic metaflammation in a rodent model of high-fat (HF)...

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Detalles Bibliográficos
Autores principales: Zhou, Feng, Zhang, Ying, Chen, Jing, Hu, Yimeng, Xu, Yancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220071/
https://www.ncbi.nlm.nih.gov/pubmed/30429827
http://dx.doi.org/10.3389/fendo.2018.00640