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Coronary Smooth Muscle Cell Calcium Dynamics: Effects of Bifurcation Angle on Atheroprone Conditions

This work investigates the effect of arterial bifurcation angulation on atherosclerosis development through in-silico simulations of coupled cell dynamics. The computational model presented here combines cellular pathways, fluid dynamics, and physiologically-realistic vessel geometries as observed i...

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Detalles Bibliográficos
Autores principales: Dowding, Stewart, Zakkaroff, Constantine, Moore, Stephen, David, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220094/
https://www.ncbi.nlm.nih.gov/pubmed/30429800
http://dx.doi.org/10.3389/fphys.2018.01528