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Microfluidics-enabled phenotyping of a whole population of C. elegans worms over their embryonic and post-embryonic development at single-organism resolution

The organism Caenorhabditis elegans is a performant model system for studying human biological processes and diseases, but until now all phenome data are produced as population-averaged read-outs. Monitoring of individual responses to drug treatments would however be more informative. Here, a new st...

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Detalles Bibliográficos
Autores principales: Letizia, Maria Cristina, Cornaglia, Matteo, Trouillon, Raphaël, Sorrentino, Vincenzo, Mouchiroud, Laurent, Bou Sleiman, Maroun S., Auwerx, Johan, Gijs, Martin A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220190/
https://www.ncbi.nlm.nih.gov/pubmed/31057896
http://dx.doi.org/10.1038/s41378-018-0003-8