PRKAA1/AMPKα1-driven glycolysis in endothelial cells exposed to disturbed flow protects against atherosclerosis

Increased aerobic glycolysis in endothelial cells of atheroprone areas of blood vessels has been hypothesized to drive increased inflammation and lesion burden but direct links remain to be established. Here we show that endothelial cells exposed to disturbed flow in vivo and in vitro exhibit increa...

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Detalles Bibliográficos
Autores principales: Yang, Qiuhua, Xu, Jiean, Ma, Qian, Liu, Zhiping, Sudhahar, Varadarajan, Cao, Yapeng, Wang, Lina, Zeng, Xianqiu, Zhou, Yaqi, Zhang, Min, Xu, Yiming, Wang, Yong, Weintraub, Neal L., Zhang, Chunxiang, Fukai, Tohru, Wu, Chaodong, Huang, Lei, Han, Zhen, Wang, Tao, Fulton, David J., Hong, Mei, Huo, Yuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220207/
https://www.ncbi.nlm.nih.gov/pubmed/30405100
http://dx.doi.org/10.1038/s41467-018-07132-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220207/
https://www.ncbi.nlm.nih.gov/pubmed/30405100
http://dx.doi.org/10.1038/s41467-018-07132-x

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