Kauniolide synthase is a P450 with unusual hydroxylation and cyclization-elimination activity

Guaianolides are an important class of sesquiterpene lactones with unique biological and pharmaceutical properties. They have been postulated to be derived from germacranolides, but for years no progress has been made in the elucidation of their biosynthesis that requires an unknown cyclization mech...

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Detalles Bibliográficos
Autores principales: Liu, Qing, Beyraghdar Kashkooli, Arman, Manzano, David, Pateraki, Irini, Richard, Lea, Kolkman, Pim, Lucas, Maria Fátima, Guallar, Victor, de Vos, Ric C.H., Franssen, Maurice C. R., van der Krol, Alexander, Bouwmeester, Harro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220293/
https://www.ncbi.nlm.nih.gov/pubmed/30405138
http://dx.doi.org/10.1038/s41467-018-06565-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220293/
https://www.ncbi.nlm.nih.gov/pubmed/30405138
http://dx.doi.org/10.1038/s41467-018-06565-8

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