Valproate reduces neuroinflammation and neuronal death in a rat chronic constriction injury model

Valproate (VPA) is a well-known drug for treating epilepsy and mania, but its action in neuropathic pain is unclear. We used a chronic constriction injury (CCI) model to explore whether VPA prevents neuropathic pain-mediated inflammation and neuronal death. Rats were treated with or without VPA. CCI...

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Detalles Bibliográficos
Autores principales: Chen, Jun-Yih, Chu, Li-Wen, Cheng, Kuang-I, Hsieh, Su-Ling, Juan, Yung-Shun, Wu, Bin-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220313/
https://www.ncbi.nlm.nih.gov/pubmed/30405207
http://dx.doi.org/10.1038/s41598-018-34915-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220313/
https://www.ncbi.nlm.nih.gov/pubmed/30405207
http://dx.doi.org/10.1038/s41598-018-34915-5

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