EGFR is required for FOS‐dependent bone tumor development via RSK2/CREB signaling

Osteosarcoma (OS) is a rare tumor of the bone occurring mainly in young adults accounting for 5% of all childhood cancers. Because of the limited therapeutic options, there has been no survival improvement for OS patients in the past 40 years. The epidermal growth factor receptor (EGFR) is highly ex...

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Detalles Bibliográficos
Autores principales: Linder, Markus, Glitzner, Elisabeth, Srivatsa, Sriram, Bakiri, Latifa, Matsuoka, Kazuhiko, Shahrouzi, Parastoo, Dumanic, Monika, Novoszel, Philipp, Mohr, Thomas, Langer, Oliver, Wanek, Thomas, Mitterhauser, Markus, Wagner, Erwin F, Sibilia, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220323/
https://www.ncbi.nlm.nih.gov/pubmed/30361264
http://dx.doi.org/10.15252/emmm.201809408

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