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Cancer cell adaptation to hypoxia involves a HIF‐GPRC5A‐YAP axis

Hypoxia is a hallmark of solid tumours and a key physiological feature distinguishing cancer from normal tissue. However, a major challenge remains in identifying tractable molecular targets that hypoxic cancer cells depend on for survival. Here, we used SILAC‐based proteomics to identify the orphan...

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Detalles Bibliográficos
Autores principales:	Greenhough, Alexander, Bagley, Clare, Heesom, Kate J, Gurevich, David B, Gay, David, Bond, Mark, Collard, Tracey J, Paraskeva, Chris, Martin, Paul, Sansom, Owen J, Malik, Karim, Williams, Ann C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220329/ https://www.ncbi.nlm.nih.gov/pubmed/30143543 http://dx.doi.org/10.15252/emmm.201708699

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