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HMBG1 as a Driver of Inflammatory and Immune Processes in the Pathogenesis of Ocular Diseases
High-mobility group box 1 (HMGB1) is a nuclear protein that can also act as an extracellular trigger of inflammation, proliferation, and migration in eye diseases. It induces signaling pathways by binding to the receptor for advanced glycation end products (RAGE) and Toll-like receptors (TLRs) 2, 4,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220384/ https://www.ncbi.nlm.nih.gov/pubmed/30473885 http://dx.doi.org/10.1155/2018/5195290 |