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Benchmarking Tree and Ancestral Sequence Inference for B Cell Receptor Sequences

B cell receptor sequences evolve during affinity maturation according to a Darwinian process of mutation and selection. Phylogenetic tools are used extensively to reconstruct ancestral sequences and phylogenetic trees from affinity-matured sequences. In addition to using general-purpose phylogenetic...

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Detalles Bibliográficos
Autores principales:	Davidsen, Kristian, Matsen, Frederick A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220437/ https://www.ncbi.nlm.nih.gov/pubmed/30429847 http://dx.doi.org/10.3389/fimmu.2018.02451

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