Ibuprofen prevents progression of ataxia telangiectasia symptoms in ATM-deficient mice

BACKGROUND: Inflammation plays a critical role in accelerating the progression of neurodegenerative diseases, such as Alzheimer’s disease (AD) and ataxia telangiectasia (A-T). In A-T mouse models, LPS-induced neuroinflammation advances the degenerative changes found in cerebellar Purkinje neurons bo...

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Detalles Bibliográficos
Autores principales: Hui, Chin Wai, Song, Xuan, Ma, Fulin, Shen, Xuting, Herrup, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220455/
https://www.ncbi.nlm.nih.gov/pubmed/30400801
http://dx.doi.org/10.1186/s12974-018-1338-7

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