Satellite cells maintain regenerative capacity but fail to repair disease-associated muscle damage in mice with Pompe disease

Pompe disease is a metabolic myopathy that is caused by glycogen accumulation as a result of deficiency of the lysosomal enzyme acid alpha glucosidase (GAA). Previously, we showed that adult muscle stem cells termed satellite cells are present at normal levels in muscle from patients with Pompe dise...

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Detalles Bibliográficos
Autores principales: Schaaf, Gerben J., van Gestel, Tom J. M., in ‘t Groen, Stijn L. M., de Jong, Bart, Boomaars, Björn, Tarallo, Antonietta, Cardone, Monica, Parenti, Giancarlo, van der Ploeg, Ans T., Pijnappel, W. W. M. Pim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220463/
https://www.ncbi.nlm.nih.gov/pubmed/30404653
http://dx.doi.org/10.1186/s40478-018-0620-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220463/
https://www.ncbi.nlm.nih.gov/pubmed/30404653
http://dx.doi.org/10.1186/s40478-018-0620-3

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