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Knomics-Biota - a system for exploratory analysis of human gut microbiota data
BACKGROUND: Metagenomic surveys of human microbiota are becoming increasingly widespread in academic research as well as in food and pharmaceutical industries and clinical context. Intuitive tools for investigating experimental data are of high interest to researchers. RESULTS: Knomics-Biota is a we...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220475/ https://www.ncbi.nlm.nih.gov/pubmed/30450127 http://dx.doi.org/10.1186/s13040-018-0187-3 |
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author | Efimova, Daria Tyakht, Alexander Popenko, Anna Vasilyev, Anatoly Altukhov, Ilya Dovidchenko, Nikita Odintsova, Vera Klimenko, Natalya Loshkarev, Robert Pashkova, Maria Elizarova, Anna Voroshilova, Viktoriya Slavskii, Sergei Pekov, Yury Filippova, Ekaterina Shashkova, Tatiana Levin, Evgenii Alexeev, Dmitry |
author_facet | Efimova, Daria Tyakht, Alexander Popenko, Anna Vasilyev, Anatoly Altukhov, Ilya Dovidchenko, Nikita Odintsova, Vera Klimenko, Natalya Loshkarev, Robert Pashkova, Maria Elizarova, Anna Voroshilova, Viktoriya Slavskii, Sergei Pekov, Yury Filippova, Ekaterina Shashkova, Tatiana Levin, Evgenii Alexeev, Dmitry |
author_sort | Efimova, Daria |
collection | PubMed |
description | BACKGROUND: Metagenomic surveys of human microbiota are becoming increasingly widespread in academic research as well as in food and pharmaceutical industries and clinical context. Intuitive tools for investigating experimental data are of high interest to researchers. RESULTS: Knomics-Biota is a web-based resource for exploratory analysis of human gut metagenomes. Users can generate and share analytical reports corresponding to common experimental schemes (like case-control study or paired comparison). Interactive visualizations and statistical analysis are provided in association with the external factors and in the context of thousands of publicly available datasets arranged into thematic collections. The web-service is available at https://biota.knomics.ru. CONCLUSIONS: Knomics-Biota web service is a comprehensive tool for interactive metagenomic data analysis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13040-018-0187-3) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-6220475 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-62204752018-11-16 Knomics-Biota - a system for exploratory analysis of human gut microbiota data Efimova, Daria Tyakht, Alexander Popenko, Anna Vasilyev, Anatoly Altukhov, Ilya Dovidchenko, Nikita Odintsova, Vera Klimenko, Natalya Loshkarev, Robert Pashkova, Maria Elizarova, Anna Voroshilova, Viktoriya Slavskii, Sergei Pekov, Yury Filippova, Ekaterina Shashkova, Tatiana Levin, Evgenii Alexeev, Dmitry BioData Min Software Article BACKGROUND: Metagenomic surveys of human microbiota are becoming increasingly widespread in academic research as well as in food and pharmaceutical industries and clinical context. Intuitive tools for investigating experimental data are of high interest to researchers. RESULTS: Knomics-Biota is a web-based resource for exploratory analysis of human gut metagenomes. Users can generate and share analytical reports corresponding to common experimental schemes (like case-control study or paired comparison). Interactive visualizations and statistical analysis are provided in association with the external factors and in the context of thousands of publicly available datasets arranged into thematic collections. The web-service is available at https://biota.knomics.ru. CONCLUSIONS: Knomics-Biota web service is a comprehensive tool for interactive metagenomic data analysis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13040-018-0187-3) contains supplementary material, which is available to authorized users. BioMed Central 2018-11-06 /pmc/articles/PMC6220475/ /pubmed/30450127 http://dx.doi.org/10.1186/s13040-018-0187-3 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Software Article Efimova, Daria Tyakht, Alexander Popenko, Anna Vasilyev, Anatoly Altukhov, Ilya Dovidchenko, Nikita Odintsova, Vera Klimenko, Natalya Loshkarev, Robert Pashkova, Maria Elizarova, Anna Voroshilova, Viktoriya Slavskii, Sergei Pekov, Yury Filippova, Ekaterina Shashkova, Tatiana Levin, Evgenii Alexeev, Dmitry Knomics-Biota - a system for exploratory analysis of human gut microbiota data |
title | Knomics-Biota - a system for exploratory analysis of human gut microbiota data |
title_full | Knomics-Biota - a system for exploratory analysis of human gut microbiota data |
title_fullStr | Knomics-Biota - a system for exploratory analysis of human gut microbiota data |
title_full_unstemmed | Knomics-Biota - a system for exploratory analysis of human gut microbiota data |
title_short | Knomics-Biota - a system for exploratory analysis of human gut microbiota data |
title_sort | knomics-biota - a system for exploratory analysis of human gut microbiota data |
topic | Software Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220475/ https://www.ncbi.nlm.nih.gov/pubmed/30450127 http://dx.doi.org/10.1186/s13040-018-0187-3 |
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