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Induced B Cell Development in Adult Mice

We employed the B-Indu-Rag1 model in which the coding exon of recombination-activating gene 1 (Rag1) is inactivated by inversion. It is flanked by inverted loxP sites. Accordingly, B cell development is stopped at the pro/pre B-I cell precursor stage. A B cell-specific Cre recombinase fused to a mut...

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Detalles Bibliográficos
Autores principales:	Brennecke, Anne-Margarete, Düber, Sandra, Roy, Bishnudeo, Thomsen, Irene, Garbe, Annette I., Klawonn, Frank, Pabst, Oliver, Kretschmer, Karsten, Weiss, Siegfried
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220648/ https://www.ncbi.nlm.nih.gov/pubmed/30429851 http://dx.doi.org/10.3389/fimmu.2018.02483

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