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FACTORS RELATED TO AMPUTATION LEVEL AND WOUND HEALING IN DIABETIC PATIENTS

OBJECTIVE: There are no specific criteria that define the level of amputation in diabetic patients. The objective of this study was to assess the influence of clinical and laboratory parameters in determining the level of amputation and the wound healing time. METHODS: One hundred and thirty-nine di...

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Autores principales: Baumfeld, Daniel, Baumfeld, Tiago, Macedo, Benjamim, Zambelli, Roberto, Lopes, Fernando, Nery, Caio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: ATHA EDITORA 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220668/
https://www.ncbi.nlm.nih.gov/pubmed/30464719
http://dx.doi.org/10.1590/1413-785220182605173445
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author Baumfeld, Daniel
Baumfeld, Tiago
Macedo, Benjamim
Zambelli, Roberto
Lopes, Fernando
Nery, Caio
author_facet Baumfeld, Daniel
Baumfeld, Tiago
Macedo, Benjamim
Zambelli, Roberto
Lopes, Fernando
Nery, Caio
author_sort Baumfeld, Daniel
collection PubMed
description OBJECTIVE: There are no specific criteria that define the level of amputation in diabetic patients. The objective of this study was to assess the influence of clinical and laboratory parameters in determining the level of amputation and the wound healing time. METHODS: One hundred and thirty-nine diabetic patients were retrospectively assessed. They underwent surgical procedures due to infection and/or ischemic necrosis. Type of surgery, antibiotic use, laboratory parameters and length of hospital stay were evaluated in this study. RESULTS: The most common amputation level was transmetatarsal, occurring in 26 patients (28.9%). The wound healing time increased with statistical significance in individuals undergoing debridement, who did not receive preoperative antibiotics and did not undergo vascular intervention. Higher levels of amputation were statistically related to limb ischemia, previous amputation and non-use of preoperative antibiotics. CONCLUSION: Patients with minor amputations undergo stump revision surgery more often, but the act of always targeting the most distal stump possible decreases energy expenditure while walking, allowing patients to achieve better quality of life. Risk factors for major amputations were ischemia and previous amputations. A protective factor was preoperative antibiotic therapy. Level of Evidence III, Retrospective Study.
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spelling pubmed-62206682018-11-21 FACTORS RELATED TO AMPUTATION LEVEL AND WOUND HEALING IN DIABETIC PATIENTS Baumfeld, Daniel Baumfeld, Tiago Macedo, Benjamim Zambelli, Roberto Lopes, Fernando Nery, Caio Acta Ortop Bras Original Article OBJECTIVE: There are no specific criteria that define the level of amputation in diabetic patients. The objective of this study was to assess the influence of clinical and laboratory parameters in determining the level of amputation and the wound healing time. METHODS: One hundred and thirty-nine diabetic patients were retrospectively assessed. They underwent surgical procedures due to infection and/or ischemic necrosis. Type of surgery, antibiotic use, laboratory parameters and length of hospital stay were evaluated in this study. RESULTS: The most common amputation level was transmetatarsal, occurring in 26 patients (28.9%). The wound healing time increased with statistical significance in individuals undergoing debridement, who did not receive preoperative antibiotics and did not undergo vascular intervention. Higher levels of amputation were statistically related to limb ischemia, previous amputation and non-use of preoperative antibiotics. CONCLUSION: Patients with minor amputations undergo stump revision surgery more often, but the act of always targeting the most distal stump possible decreases energy expenditure while walking, allowing patients to achieve better quality of life. Risk factors for major amputations were ischemia and previous amputations. A protective factor was preoperative antibiotic therapy. Level of Evidence III, Retrospective Study. ATHA EDITORA 2018 /pmc/articles/PMC6220668/ /pubmed/30464719 http://dx.doi.org/10.1590/1413-785220182605173445 Text en https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Baumfeld, Daniel
Baumfeld, Tiago
Macedo, Benjamim
Zambelli, Roberto
Lopes, Fernando
Nery, Caio
FACTORS RELATED TO AMPUTATION LEVEL AND WOUND HEALING IN DIABETIC PATIENTS
title FACTORS RELATED TO AMPUTATION LEVEL AND WOUND HEALING IN DIABETIC PATIENTS
title_full FACTORS RELATED TO AMPUTATION LEVEL AND WOUND HEALING IN DIABETIC PATIENTS
title_fullStr FACTORS RELATED TO AMPUTATION LEVEL AND WOUND HEALING IN DIABETIC PATIENTS
title_full_unstemmed FACTORS RELATED TO AMPUTATION LEVEL AND WOUND HEALING IN DIABETIC PATIENTS
title_short FACTORS RELATED TO AMPUTATION LEVEL AND WOUND HEALING IN DIABETIC PATIENTS
title_sort factors related to amputation level and wound healing in diabetic patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220668/
https://www.ncbi.nlm.nih.gov/pubmed/30464719
http://dx.doi.org/10.1590/1413-785220182605173445
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