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Hypoxia negatively affects senescence in osteoclasts and delays osteoclastogenesis
Cellular senescence, that is, the withdrawal from the cell cycle, combined with the acquirement of the senescence associated secretory phenotype has important roles during health and disease and is essential for tissue remodeling during embryonic development. Osteoclasts are multinucleated cells, re...
Autores principales: | Gorissen, Ben, de Bruin, Alain, Miranda‐Bedate, Alberto, Korthagen, Nicoline, Wolschrijn, Claudia, de Vries, Teun J., van Weeren, René, Tryfonidou, Marianna A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220985/ https://www.ncbi.nlm.nih.gov/pubmed/29932209 http://dx.doi.org/10.1002/jcp.26511 |
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