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Biglycan Intensifies ALK5–Smad2/3 Signaling by TGF‐β(1) and Downregulates Syndecan‐4 in Cultured Vascular Endothelial Cells

Proteoglycans are macromolecules that consist of a core protein and one or more glycosaminoglycan side chains. A small leucine‐rich dermatan sulfate proteoglycan, biglycan, is one of the predominant types of proteoglycans synthesized by vascular endothelial cells; however, the physiological function...

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Detalles Bibliográficos
Autores principales: Hara, Takato, Yoshida, Eiko, Shinkai, Yasuhiro, Yamamoto, Chika, Fujiwara, Yasuyuki, Kumagai, Yoshito, Kaji, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221004/
https://www.ncbi.nlm.nih.gov/pubmed/27585241
http://dx.doi.org/10.1002/jcb.25721