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VEGF receptor‐2/neuropilin 1 trans‐complex formation between endothelial and tumor cells is an independent predictor of pancreatic cancer survival

Unstable and dysfunctional tumor vasculature promotes cancer progression and spread. Signal transduction by the pro‐angiogenic vascular endothelial growth factor (VEGF) receptor‐2 (VEGFR2) is modulated by VEGFA‐dependent complex formation with neuropilin 1 (NRP1). NRP1 expressed on tumor cells can f...

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Detalles Bibliográficos
Autores principales: Morin, Eric, Sjöberg, Elin, Tjomsland, Vegard, Testini, Chiara, Lindskog, Cecilia, Franklin, Oskar, Sund, Malin, Öhlund, Daniel, Kiflemariam, Sara, Sjöblom, Tobias, Claesson‐Welsh, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221118/
https://www.ncbi.nlm.nih.gov/pubmed/30027561
http://dx.doi.org/10.1002/path.5141

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