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VEGF receptor‐2/neuropilin 1 trans‐complex formation between endothelial and tumor cells is an independent predictor of pancreatic cancer survival
Unstable and dysfunctional tumor vasculature promotes cancer progression and spread. Signal transduction by the pro‐angiogenic vascular endothelial growth factor (VEGF) receptor‐2 (VEGFR2) is modulated by VEGFA‐dependent complex formation with neuropilin 1 (NRP1). NRP1 expressed on tumor cells can f...
Autores principales: | Morin, Eric, Sjöberg, Elin, Tjomsland, Vegard, Testini, Chiara, Lindskog, Cecilia, Franklin, Oskar, Sund, Malin, Öhlund, Daniel, Kiflemariam, Sara, Sjöblom, Tobias, Claesson‐Welsh, Lena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221118/ https://www.ncbi.nlm.nih.gov/pubmed/30027561 http://dx.doi.org/10.1002/path.5141 |
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