In vivo characterization of white matter pathology in premanifest huntington's disease

OBJECTIVE: Huntington's disease (HD) is a monogenic, fully penetrant neurodegenerative disorder, providing an ideal model for understanding brain changes occurring in the years prior to disease onset. Diffusion tensor imaging (DTI) studies show widespread white matter disorganization in the ear...

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Detalles Bibliográficos
Autores principales: Zhang, Jiaying, Gregory, Sarah, Scahill, Rachael I., Durr, Alexandra, Thomas, David L., Lehericy, Stéphane, Rees, Geraint, Tabrizi, Sarah J., Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221120/
https://www.ncbi.nlm.nih.gov/pubmed/30063250
http://dx.doi.org/10.1002/ana.25309

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