Fluconazole‐induced actin cytoskeleton remodeling requires phosphatidylinositol 3‐phosphate 5‐kinase in the pathogenic yeast Candida glabrata

Known azole antifungal resistance mechanisms include mitochondrial dysfunction and overexpression of the sterol biosynthetic target enzyme and multidrug efflux pumps. Here, we identify, through a genetic screen, the vacuolar membrane‐resident phosphatidylinositol 3‐phosphate 5‐kinase (CgFab1) to be...

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Detalles Bibliográficos
Autores principales: Bhakt, Priyanka, Shivarathri, Raju, Choudhary, Deepak Kumar, Borah, Sapan, Kaur, Rupinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221164/
https://www.ncbi.nlm.nih.gov/pubmed/30137648
http://dx.doi.org/10.1111/mmi.14110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221164/
https://www.ncbi.nlm.nih.gov/pubmed/30137648
http://dx.doi.org/10.1111/mmi.14110

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