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Fluconazole‐induced actin cytoskeleton remodeling requires phosphatidylinositol 3‐phosphate 5‐kinase in the pathogenic yeast Candida glabrata
Known azole antifungal resistance mechanisms include mitochondrial dysfunction and overexpression of the sterol biosynthetic target enzyme and multidrug efflux pumps. Here, we identify, through a genetic screen, the vacuolar membrane‐resident phosphatidylinositol 3‐phosphate 5‐kinase (CgFab1) to be...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221164/ https://www.ncbi.nlm.nih.gov/pubmed/30137648 http://dx.doi.org/10.1111/mmi.14110 |