DNMTs and SETDB1 function as co-repressors in MAX-mediated repression of germ cell–related genes in mouse embryonic stem cells

In embryonic stem cells (ESCs), the expression of development-related genes, including germ cell–related genes, is globally repressed. The transcription factor MAX represses germ cell–related gene expression in ESCs via PCGF6-polycomb repressive complex 1 (PRC1), which consists of several epigenetic...

Descripción completa

Detalles Bibliográficos
Autores principales: Tatsumi, Daiki, Hayashi, Yohei, Endo, Mai, Kobayashi, Hisato, Yoshioka, Takumi, Kiso, Kohei, Kanno, Shinichiro, Nakai, Yuji, Maeda, Ikuma, Mochizuki, Kentaro, Tachibana, Makoto, Koseki, Haruhiko, Okuda, Akihiko, Yasui, Akira, Kono, Tomohiro, Matsui, Yasuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221296/
https://www.ncbi.nlm.nih.gov/pubmed/30403691
http://dx.doi.org/10.1371/journal.pone.0205969

Ejemplares similares

Ejemplares similares