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CXXC1 is not essential for normal DNA double-strand break formation and meiotic recombination in mouse

In most mammals, including mice and humans, meiotic recombination is determined by the meiosis specific histone methytransferase PRDM9, which binds to specific DNA sequences and trimethylates histone 3 at lysine-4 and lysine-36 at the adjacent nucleosomes. These actions ensure successful DNA double...

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Detalles Bibliográficos
Autores principales:	Tian, Hui, Billings, Timothy, Petkov, Petko M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221362/ https://www.ncbi.nlm.nih.gov/pubmed/30365547 http://dx.doi.org/10.1371/journal.pgen.1007657

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