Cargando…

Non-insidious Large Joint Manifestation of Severe Cachectic Rheumatoid Arthritis

Rheumatoid arthritis (RA) is an autoimmune disorder in which constitutional symptoms typically occur before joint swelling becomes a true clinical phenomenon. Weight loss, although common, is generally mild in nature and occurs after long standing inflammation. While large joints do become inflamed,...

Descripción completa

Detalles Bibliográficos
Autores principales: Weissman, Simcha, Alsheikh, Mira, Kamar, Khalil, Breslin, Joshua, Khabut, Anthony, Maruf, Mohammad G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221515/
https://www.ncbi.nlm.nih.gov/pubmed/30430055
http://dx.doi.org/10.7759/cureus.3266
_version_ 1783369035677696000
author Weissman, Simcha
Alsheikh, Mira
Kamar, Khalil
Breslin, Joshua
Khabut, Anthony
Maruf, Mohammad G
author_facet Weissman, Simcha
Alsheikh, Mira
Kamar, Khalil
Breslin, Joshua
Khabut, Anthony
Maruf, Mohammad G
author_sort Weissman, Simcha
collection PubMed
description Rheumatoid arthritis (RA) is an autoimmune disorder in which constitutional symptoms typically occur before joint swelling becomes a true clinical phenomenon. Weight loss, although common, is generally mild in nature and occurs after long standing inflammation. While large joints do become inflamed, RA has a much stronger predilection for the small joints. Our case is a rarity in the fact that there was initial large joint swelling without long standing inflammation. Additionally, the weight loss was cachectic in nature and extreme. Furthermore, while extra-articular manifestations do commonly occur, spontaneous pneumothorax is certainly atypical. The content of this manuscript serves to enlighten hospitalist physicians and residents, as to the odd way in which a case like this may present.
format Online
Article
Text
id pubmed-6221515
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-62215152018-11-14 Non-insidious Large Joint Manifestation of Severe Cachectic Rheumatoid Arthritis Weissman, Simcha Alsheikh, Mira Kamar, Khalil Breslin, Joshua Khabut, Anthony Maruf, Mohammad G Cureus Internal Medicine Rheumatoid arthritis (RA) is an autoimmune disorder in which constitutional symptoms typically occur before joint swelling becomes a true clinical phenomenon. Weight loss, although common, is generally mild in nature and occurs after long standing inflammation. While large joints do become inflamed, RA has a much stronger predilection for the small joints. Our case is a rarity in the fact that there was initial large joint swelling without long standing inflammation. Additionally, the weight loss was cachectic in nature and extreme. Furthermore, while extra-articular manifestations do commonly occur, spontaneous pneumothorax is certainly atypical. The content of this manuscript serves to enlighten hospitalist physicians and residents, as to the odd way in which a case like this may present. Cureus 2018-09-07 /pmc/articles/PMC6221515/ /pubmed/30430055 http://dx.doi.org/10.7759/cureus.3266 Text en Copyright © 2018, Weissman et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Weissman, Simcha
Alsheikh, Mira
Kamar, Khalil
Breslin, Joshua
Khabut, Anthony
Maruf, Mohammad G
Non-insidious Large Joint Manifestation of Severe Cachectic Rheumatoid Arthritis
title Non-insidious Large Joint Manifestation of Severe Cachectic Rheumatoid Arthritis
title_full Non-insidious Large Joint Manifestation of Severe Cachectic Rheumatoid Arthritis
title_fullStr Non-insidious Large Joint Manifestation of Severe Cachectic Rheumatoid Arthritis
title_full_unstemmed Non-insidious Large Joint Manifestation of Severe Cachectic Rheumatoid Arthritis
title_short Non-insidious Large Joint Manifestation of Severe Cachectic Rheumatoid Arthritis
title_sort non-insidious large joint manifestation of severe cachectic rheumatoid arthritis
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221515/
https://www.ncbi.nlm.nih.gov/pubmed/30430055
http://dx.doi.org/10.7759/cureus.3266
work_keys_str_mv AT weissmansimcha noninsidiouslargejointmanifestationofseverecachecticrheumatoidarthritis
AT alsheikhmira noninsidiouslargejointmanifestationofseverecachecticrheumatoidarthritis
AT kamarkhalil noninsidiouslargejointmanifestationofseverecachecticrheumatoidarthritis
AT breslinjoshua noninsidiouslargejointmanifestationofseverecachecticrheumatoidarthritis
AT khabutanthony noninsidiouslargejointmanifestationofseverecachecticrheumatoidarthritis
AT marufmohammadg noninsidiouslargejointmanifestationofseverecachecticrheumatoidarthritis