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Non-insidious Large Joint Manifestation of Severe Cachectic Rheumatoid Arthritis
Rheumatoid arthritis (RA) is an autoimmune disorder in which constitutional symptoms typically occur before joint swelling becomes a true clinical phenomenon. Weight loss, although common, is generally mild in nature and occurs after long standing inflammation. While large joints do become inflamed,...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221515/ https://www.ncbi.nlm.nih.gov/pubmed/30430055 http://dx.doi.org/10.7759/cureus.3266 |
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author | Weissman, Simcha Alsheikh, Mira Kamar, Khalil Breslin, Joshua Khabut, Anthony Maruf, Mohammad G |
author_facet | Weissman, Simcha Alsheikh, Mira Kamar, Khalil Breslin, Joshua Khabut, Anthony Maruf, Mohammad G |
author_sort | Weissman, Simcha |
collection | PubMed |
description | Rheumatoid arthritis (RA) is an autoimmune disorder in which constitutional symptoms typically occur before joint swelling becomes a true clinical phenomenon. Weight loss, although common, is generally mild in nature and occurs after long standing inflammation. While large joints do become inflamed, RA has a much stronger predilection for the small joints. Our case is a rarity in the fact that there was initial large joint swelling without long standing inflammation. Additionally, the weight loss was cachectic in nature and extreme. Furthermore, while extra-articular manifestations do commonly occur, spontaneous pneumothorax is certainly atypical. The content of this manuscript serves to enlighten hospitalist physicians and residents, as to the odd way in which a case like this may present. |
format | Online Article Text |
id | pubmed-6221515 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-62215152018-11-14 Non-insidious Large Joint Manifestation of Severe Cachectic Rheumatoid Arthritis Weissman, Simcha Alsheikh, Mira Kamar, Khalil Breslin, Joshua Khabut, Anthony Maruf, Mohammad G Cureus Internal Medicine Rheumatoid arthritis (RA) is an autoimmune disorder in which constitutional symptoms typically occur before joint swelling becomes a true clinical phenomenon. Weight loss, although common, is generally mild in nature and occurs after long standing inflammation. While large joints do become inflamed, RA has a much stronger predilection for the small joints. Our case is a rarity in the fact that there was initial large joint swelling without long standing inflammation. Additionally, the weight loss was cachectic in nature and extreme. Furthermore, while extra-articular manifestations do commonly occur, spontaneous pneumothorax is certainly atypical. The content of this manuscript serves to enlighten hospitalist physicians and residents, as to the odd way in which a case like this may present. Cureus 2018-09-07 /pmc/articles/PMC6221515/ /pubmed/30430055 http://dx.doi.org/10.7759/cureus.3266 Text en Copyright © 2018, Weissman et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Weissman, Simcha Alsheikh, Mira Kamar, Khalil Breslin, Joshua Khabut, Anthony Maruf, Mohammad G Non-insidious Large Joint Manifestation of Severe Cachectic Rheumatoid Arthritis |
title | Non-insidious Large Joint Manifestation of Severe Cachectic Rheumatoid Arthritis |
title_full | Non-insidious Large Joint Manifestation of Severe Cachectic Rheumatoid Arthritis |
title_fullStr | Non-insidious Large Joint Manifestation of Severe Cachectic Rheumatoid Arthritis |
title_full_unstemmed | Non-insidious Large Joint Manifestation of Severe Cachectic Rheumatoid Arthritis |
title_short | Non-insidious Large Joint Manifestation of Severe Cachectic Rheumatoid Arthritis |
title_sort | non-insidious large joint manifestation of severe cachectic rheumatoid arthritis |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221515/ https://www.ncbi.nlm.nih.gov/pubmed/30430055 http://dx.doi.org/10.7759/cureus.3266 |
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