Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity

The mammalian imprinted Dlk1-Dio3 locus produces multiple long non-coding RNAs (lncRNAs) from the maternally inherited allele, including Meg3 (i.e., Gtl2) in the mammalian genome. Although this locus has well-characterized functions in stem cell and tumor contexts, its role during neural development...

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Detalles Bibliográficos
Autores principales: Yen, Ya-Ping, Hsieh, Wen-Fu, Tsai, Ya-Yin, Lu, Ya-Lin, Liau, Ee Shan, Hsu, Ho-Chiang, Chen, Yen-Chung, Liu, Ting-Chun, Chang, Mien, Li, Joye, Lin, Shau-Ping, Hung, Jui-Hung, Chen, Jun-An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221546/
https://www.ncbi.nlm.nih.gov/pubmed/30311912
http://dx.doi.org/10.7554/eLife.38080

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