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Cardiac tamponade induced by dabrafenib and trametinib combination therapy for melanoma: Case report

RATIONALE: BRAF and MEK inhibitors (BRAF/MEKi) are targeted therapy for proto-oncogene BRAF mutated metastatic unresectable melanoma. Compared to monotherapy, an increased cardiovascular toxicity is reported with the combination of Dabrafenib and Trametinib. This case report documents Grade 4 cardia...

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Detalles Bibliográficos
Autores principales:	Sundaram, Vinita Ruth, Abbas, Tahir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221704/ https://www.ncbi.nlm.nih.gov/pubmed/30383630 http://dx.doi.org/10.1097/MD.0000000000012751

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