Cargando…

Do Corticosteroids Still Have a Place in the Treatment of Chronic Pain?

Corticosteroids have played a standard role in the multimodal pain management in the treatment of chronic spinal pain (cervical and lumbar) and osteoarthritis pain over the past three decades. In this review we discuss different types of injectable steroids that are mainly used for injection into th...

Descripción completa

Detalles Bibliográficos
Autores principales: Knezevic, Nebojsa Nick, Jovanovic, Filip, Voronov, Dimitry, Candido, Kenneth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221932/
https://www.ncbi.nlm.nih.gov/pubmed/30443214
http://dx.doi.org/10.3389/fphar.2018.01229
_version_ 1783369109792096256
author Knezevic, Nebojsa Nick
Jovanovic, Filip
Voronov, Dimitry
Candido, Kenneth D.
author_facet Knezevic, Nebojsa Nick
Jovanovic, Filip
Voronov, Dimitry
Candido, Kenneth D.
author_sort Knezevic, Nebojsa Nick
collection PubMed
description Corticosteroids have played a standard role in the multimodal pain management in the treatment of chronic spinal pain (cervical and lumbar) and osteoarthritis pain over the past three decades. In this review we discuss different types of injectable steroids that are mainly used for injection into the epidural space (for the treatment of radicular back and neck pain), and as intra-articular injections for different types of osteoarthritis related pain conditions. Furthermore, we discuss different approaches taken for epidural corticosteroid injections and spinal surgical rates when injections fail to resolve painful conditions, as well as the possibility of using local anesthetics alone for neuraxial injections, instead of in combination with corticosteroids. While we present some beneficial effects of newly available treatment options for low back pain and osteoarthritis pain, such as use of PRP and hyaluronic acid, corticosteroids remain important considerations in the management of these chronic pain conditions.
format Online
Article
Text
id pubmed-6221932
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-62219322018-11-15 Do Corticosteroids Still Have a Place in the Treatment of Chronic Pain? Knezevic, Nebojsa Nick Jovanovic, Filip Voronov, Dimitry Candido, Kenneth D. Front Pharmacol Pharmacology Corticosteroids have played a standard role in the multimodal pain management in the treatment of chronic spinal pain (cervical and lumbar) and osteoarthritis pain over the past three decades. In this review we discuss different types of injectable steroids that are mainly used for injection into the epidural space (for the treatment of radicular back and neck pain), and as intra-articular injections for different types of osteoarthritis related pain conditions. Furthermore, we discuss different approaches taken for epidural corticosteroid injections and spinal surgical rates when injections fail to resolve painful conditions, as well as the possibility of using local anesthetics alone for neuraxial injections, instead of in combination with corticosteroids. While we present some beneficial effects of newly available treatment options for low back pain and osteoarthritis pain, such as use of PRP and hyaluronic acid, corticosteroids remain important considerations in the management of these chronic pain conditions. Frontiers Media S.A. 2018-11-01 /pmc/articles/PMC6221932/ /pubmed/30443214 http://dx.doi.org/10.3389/fphar.2018.01229 Text en Copyright © 2018 Knezevic, Jovanovic, Voronov and Candido. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Knezevic, Nebojsa Nick
Jovanovic, Filip
Voronov, Dimitry
Candido, Kenneth D.
Do Corticosteroids Still Have a Place in the Treatment of Chronic Pain?
title Do Corticosteroids Still Have a Place in the Treatment of Chronic Pain?
title_full Do Corticosteroids Still Have a Place in the Treatment of Chronic Pain?
title_fullStr Do Corticosteroids Still Have a Place in the Treatment of Chronic Pain?
title_full_unstemmed Do Corticosteroids Still Have a Place in the Treatment of Chronic Pain?
title_short Do Corticosteroids Still Have a Place in the Treatment of Chronic Pain?
title_sort do corticosteroids still have a place in the treatment of chronic pain?
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221932/
https://www.ncbi.nlm.nih.gov/pubmed/30443214
http://dx.doi.org/10.3389/fphar.2018.01229
work_keys_str_mv AT knezevicnebojsanick docorticosteroidsstillhaveaplaceinthetreatmentofchronicpain
AT jovanovicfilip docorticosteroidsstillhaveaplaceinthetreatmentofchronicpain
AT voronovdimitry docorticosteroidsstillhaveaplaceinthetreatmentofchronicpain
AT candidokennethd docorticosteroidsstillhaveaplaceinthetreatmentofchronicpain