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Do Corticosteroids Still Have a Place in the Treatment of Chronic Pain?
Corticosteroids have played a standard role in the multimodal pain management in the treatment of chronic spinal pain (cervical and lumbar) and osteoarthritis pain over the past three decades. In this review we discuss different types of injectable steroids that are mainly used for injection into th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221932/ https://www.ncbi.nlm.nih.gov/pubmed/30443214 http://dx.doi.org/10.3389/fphar.2018.01229 |
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author | Knezevic, Nebojsa Nick Jovanovic, Filip Voronov, Dimitry Candido, Kenneth D. |
author_facet | Knezevic, Nebojsa Nick Jovanovic, Filip Voronov, Dimitry Candido, Kenneth D. |
author_sort | Knezevic, Nebojsa Nick |
collection | PubMed |
description | Corticosteroids have played a standard role in the multimodal pain management in the treatment of chronic spinal pain (cervical and lumbar) and osteoarthritis pain over the past three decades. In this review we discuss different types of injectable steroids that are mainly used for injection into the epidural space (for the treatment of radicular back and neck pain), and as intra-articular injections for different types of osteoarthritis related pain conditions. Furthermore, we discuss different approaches taken for epidural corticosteroid injections and spinal surgical rates when injections fail to resolve painful conditions, as well as the possibility of using local anesthetics alone for neuraxial injections, instead of in combination with corticosteroids. While we present some beneficial effects of newly available treatment options for low back pain and osteoarthritis pain, such as use of PRP and hyaluronic acid, corticosteroids remain important considerations in the management of these chronic pain conditions. |
format | Online Article Text |
id | pubmed-6221932 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-62219322018-11-15 Do Corticosteroids Still Have a Place in the Treatment of Chronic Pain? Knezevic, Nebojsa Nick Jovanovic, Filip Voronov, Dimitry Candido, Kenneth D. Front Pharmacol Pharmacology Corticosteroids have played a standard role in the multimodal pain management in the treatment of chronic spinal pain (cervical and lumbar) and osteoarthritis pain over the past three decades. In this review we discuss different types of injectable steroids that are mainly used for injection into the epidural space (for the treatment of radicular back and neck pain), and as intra-articular injections for different types of osteoarthritis related pain conditions. Furthermore, we discuss different approaches taken for epidural corticosteroid injections and spinal surgical rates when injections fail to resolve painful conditions, as well as the possibility of using local anesthetics alone for neuraxial injections, instead of in combination with corticosteroids. While we present some beneficial effects of newly available treatment options for low back pain and osteoarthritis pain, such as use of PRP and hyaluronic acid, corticosteroids remain important considerations in the management of these chronic pain conditions. Frontiers Media S.A. 2018-11-01 /pmc/articles/PMC6221932/ /pubmed/30443214 http://dx.doi.org/10.3389/fphar.2018.01229 Text en Copyright © 2018 Knezevic, Jovanovic, Voronov and Candido. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pharmacology Knezevic, Nebojsa Nick Jovanovic, Filip Voronov, Dimitry Candido, Kenneth D. Do Corticosteroids Still Have a Place in the Treatment of Chronic Pain? |
title | Do Corticosteroids Still Have a Place in the Treatment of Chronic Pain? |
title_full | Do Corticosteroids Still Have a Place in the Treatment of Chronic Pain? |
title_fullStr | Do Corticosteroids Still Have a Place in the Treatment of Chronic Pain? |
title_full_unstemmed | Do Corticosteroids Still Have a Place in the Treatment of Chronic Pain? |
title_short | Do Corticosteroids Still Have a Place in the Treatment of Chronic Pain? |
title_sort | do corticosteroids still have a place in the treatment of chronic pain? |
topic | Pharmacology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221932/ https://www.ncbi.nlm.nih.gov/pubmed/30443214 http://dx.doi.org/10.3389/fphar.2018.01229 |
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