Defective mitochondrial protein import contributes to complex I-induced mitochondrial dysfunction and neurodegeneration in Parkinson’s disease

Mitochondria are the prime energy source in most eukaryotic cells, but these highly dynamic organelles are also involved in a multitude of cellular events. Disruption of mitochondrial homeostasis and the subsequent mitochondrial dysfunction plays a key role in the pathophysiology of Parkinson’s dise...

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Detalles Bibliográficos
Autores principales: Franco-Iborra, Sandra, Cuadros, Thais, Parent, Annabelle, Romero-Gimenez, Jordi, Vila, Miquel, Perier, Celine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221944/
https://www.ncbi.nlm.nih.gov/pubmed/30405116
http://dx.doi.org/10.1038/s41419-018-1154-0

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