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Long Pentraxin 3-Mediated Fibroblast Growth Factor Trapping Impairs Fibrosarcoma Growth
Fibrosarcomas are soft tissue mesenchymal tumors originating from transformed fibroblasts. Fibroblast growth factor-2 (FGF2) and its tyrosine-kinase receptors (FGFRs) play pivotal roles in fibrosarcoma onset and progression, FGF2 being actively produced by fibroblasts in all stages along their malig...
Autores principales: | Rodrigues, Priscila Fabiana, Matarazzo, Sara, Maccarinelli, Federica, Foglio, Eleonora, Giacomini, Arianna, Silva Nunes, João Paulo, Presta, Marco, Dias, Adriana Abalen Martins, Ronca, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221954/ https://www.ncbi.nlm.nih.gov/pubmed/30443492 http://dx.doi.org/10.3389/fonc.2018.00472 |
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