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Differential Activity of Transcribed Enhancers in the Prefrontal Cortex of 537 cases with Schizophrenia and Controls

Transcription at enhancers is a widespread phenomenon which produces so-called enhancer RNA (eRNA) and occurs in an activity dependent manner. However, the role of eRNA and its utility in exploring disease-associated changes in enhancer function, and the downstream coding transcripts that they regul...

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Detalles Bibliográficos
Autores principales: Hauberg, Mads E., Fullard, John F., Zhu, Lingxue, Cohain, Ariella, Giambartolomei, Claudia, Misir, Ruth, Reach, Sarah, Johnson, Jessica S., Wang, Minghui, Mattheisen, Manuel, Børglum, Anders Dupont, Zhang, Bin, Sieberts, Solveig K., Peters, Mette A., Domenici, Enrico, Schadt, Eric E., Devlin, Bernie, Sklar, Pamela, Roeder, Kathryn, Roussos, Panos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222027/
https://www.ncbi.nlm.nih.gov/pubmed/29740122
http://dx.doi.org/10.1038/s41380-018-0059-8