Cargando…

Valproic acid as a monotherapy in drug-resistant methyl-CpG-binding protein 2 gene (MECP2) duplication-related epilepsy

Duplication of the methyl-CpG-binding protein 2 gene (MECP2) is a rare condition that results in epilepsy in half of the cases. Although this condition has been well characterized in the literature, there is a lack of research on MECP2 duplication-related epilepsy and its management. We present the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rajaprakash, Meghna, Richer, Julie, Sell, Erick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222037/ https://www.ncbi.nlm.nih.gov/pubmed/30425922 http://dx.doi.org/10.1016/j.ebcr.2018.09.009

Ejemplares similares

Methyl CpG binding protein 2 (MeCP2) enhances photodimer formation at methyl-CpG sites but suppresses dimer deamination
por: Cannistraro, Vincent J., et al.
Publicado: (2010)

5-Halogenated pyrimidine lesions within a CpG sequence context mimic 5-methylcytosine by enhancing the binding of the methyl-CpG-binding domain of methyl-CpG-binding protein 2 (MeCP2)
por: Valinluck, Victoria, et al.
Publicado: (2005)

The Epigenetic Reader Methyl-CpG-Binding Protein 2 (MeCP2) Is an Emerging Oncogene in Cancer Biology
por: Nejati-Koshki, Kazem, et al.
Publicado: (2023)

Role of DNA Methyl-CpG-Binding Protein MeCP2 in Rett Syndrome Pathobiology and Mechanism of Disease
por: Pejhan, Shervin, et al.
Publicado: (2021)

Stabilization Effect of Intrinsically Disordered Regions on Multidomain Proteins: The Case of the Methyl-CpG Protein 2, MeCP2
por: Ortega-Alarcon, David, et al.
Publicado: (2021)

Rett Syndrome and MECP2 Duplication Syndrome: Disorders of MeCP2 Dosage
por: Collins, Bridget E, et al.
Publicado: (2022)

The methyl-CpG-binding domain (MBD) is crucial for MeCP2’s dysfunction-induced defects in adult newborn neurons
por: Zhao, Na, et al.
Publicado: (2015)

Structure-specific binding of MeCP2 to four-way junction DNA through its methyl CpG-binding domain
por: Galvão, Teca Calcagno, et al.
Publicado: (2005)

Structure-specific binding of MeCP2 to four-way junction DNA through its methyl CpG-binding domain
por: Galvão, Teca Calcagno, et al.
Publicado: (2006)

Methyl-CpG-binding protein 2 (MECP2) mutation type is associated with bone disease severity in Rett syndrome
por: Caffarelli, Carla, et al.
Publicado: (2020)

MeCP2 suppresses LIN28A expression via binding to its methylated-CpG islands in pancreatic cancer cells
por: Xu, Min, et al.
Publicado: (2016)

Methyl-CpG Binding Protein 2 (Mecp2) Regulates Sensory Function Through Sema5b and Robo2
por: Leong, Wan Y., et al.
Publicado: (2015)

Early intervention with psychostimulants or antidepressants to increase methyl-CpG-binding protein 2 (MeCP2) expressions: A potential therapy for Rett syndrome
por: Pan, Chia-Ho, et al.
Publicado: (2012)

Knock-down of methyl CpG-binding protein 2 (MeCP2) causes alterations in cell proliferation and nuclear lamins expression in mammalian cells
por: Babbio, Federica, et al.
Publicado: (2012)

The Effects of O(6)-methyl Guanine DNA-methyl Transferase Promotor Methylation and CpG1, CpG2, CpG3 and CpG4 Methylation on Treatment Response and their Prognostic Significance in Patients with Glioblastoma
por: Yildiz, OG, et al.
Publicado: (2020)

Preservation of methylated CpG dinucleotides in human CpG islands
por: Panchin, Alexander Y., et al.
Publicado: (2016)

Factors to preserve CpG-rich sequences in methylated CpG islands
por: Miyahara, Hiroki, et al.
Publicado: (2015)

The Methyl-CpG Binding Proteins Mecp2, Mbd2 and Kaiso Are Dispensable for Mouse Embryogenesis, but Play a Redundant Function in Neural Differentiation
por: Martín Caballero, Isabel, et al.
Publicado: (2009)

Early life stress exacerbates behavioural and neuronal alterations in adolescent male mice lacking methyl-CpG binding protein 2 (Mecp2)
por: Torres-Pérez, Jose Vicente, et al.
Publicado: (2022)

Rett-causing mutations reveal two domains critical for MeCP2 function and for toxicity in MECP2 duplication syndrome mice
por: Heckman, Laura Dean, et al.
Publicado: (2014)

In Vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases
por: Arand, Julia, et al.
Publicado: (2012)

CpG and Non-CpG Methylation in Epigenetic Gene Regulation and Brain Function
por: Jang, Hyun Sik, et al.
Publicado: (2017)

MeCP2 duplication causes hyperandrogenism by upregulating LHCGR and downregulating RORα
por: Wang, Yu-Meng, et al.
Publicado: (2021)

Medical Comorbidities in MECP2 Duplication Syndrome: Results from the International MECP2 Duplication Database
por: Ta, Daniel, et al.
Publicado: (2022)

Duplication within two regions distal to MECP2: clinical similarity with MECP2 duplication syndrome
por: Akahoshi, Keiko, et al.
Publicado: (2023)

CpG Methylation Altered the Stability and Structure of the i-Motifs Located in the CpG Islands
por: Oshikawa, Daiki, et al.
Publicado: (2022)

Methyl-CpG Binding Protein 2 in Alzheimer Dementia
por: Kim, Baeksun, et al.
Publicado: (2019)

The Control Region of Mitochondrial DNA Shows an Unusual CpG and Non-CpG Methylation Pattern
por: Bellizzi, Dina, et al.
Publicado: (2013)

Evaluation of single CpG sites as proxies of CpG island methylation states at the genome scale
por: Barrera, Víctor, et al.
Publicado: (2012)

Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level
por: Goldsmith, Chloe, et al.
Publicado: (2021)

Sex-Based Mhrt Methylation Chromatinizes MeCP2 in the Heart
por: K.N., Harikrishnan, et al.
Publicado: (2019)

The Crucial Role of DNA Methylation and MeCP2 in Neuronal Function
por: Fasolino, Maria, et al.
Publicado: (2017)

Methyl-CpG-Binding protein 2 duplication syndrome in a Chinese patient: A case report and review of the literature
por: Xing, Xu-Hang, et al.
Publicado: (2023)

CpG Oligodeoxynucleotides for Anticancer Monotherapy from Preclinical Stages to Clinical Trials
por: Zhang, Zhongkun, et al.
Publicado: (2021)

MeCP2 and Chromatin Compartmentalization
por: Schmidt, Annika, et al.
Publicado: (2020)

Densely methylated DNA traps Methyl-CpG–binding domain protein 2 but permits free diffusion by Methyl-CpG–binding domain protein 3
por: Leighton, Gage O., et al.
Publicado: (2022)

CpG methylation signature defines human temporal lobe epilepsy and predicts drug‐resistant
por: Xiao, Wenbiao, et al.
Publicado: (2020)

Brain Region-Specific Expression of MeCP2 Isoforms Correlates with DNA Methylation within Mecp2 Regulatory Elements
por: Olson, Carl O., et al.
Publicado: (2014)

Methyl CpG binding domain protein 2 (MBD2) in inflammation
por: Lei, Qian, et al.
Publicado: (2022)

Deoxyribonucleic acid methylation profiling of single human blastocysts by methylated CpG-island amplification coupled with CpG-island microarray
por: Huntriss, John, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_vf8f6m0vottj3gkifnm7ke7gc7