Cargando…

The CDK9–cyclin T1 complex mediates saturated fatty acid–induced vascular calcification by inducing expression of the transcription factor CHOP

Vascular calcification (or mineralization) is a common complication of chronic kidney disease (CKD) and is closely associated with increased mortality and morbidity rates. We recently reported that activation of the activating transcription factor 4 (ATF4) pathway through the saturated fatty acid (S...

Descripción completa

Detalles Bibliográficos
Autores principales: Shiozaki, Yuji, Okamura, Kayo, Kohno, Shohei, Keenan, Audrey L., Williams, Kristina, Zhao, Xiaoyun, Chick, Wallace S., Miyazaki-Anzai, Shinobu, Miyazaki, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222109/
https://www.ncbi.nlm.nih.gov/pubmed/30209133
http://dx.doi.org/10.1074/jbc.RA118.004706

Ejemplares similares