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Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly
Mitochondrial reactive oxygen species (ROS) production is a tightly regulated redox signal that transmits information from the organelle to the cell. Other mitochondrial signals, such as ATP, are sensed by enzymes, including the key metabolic sensor and regulator, AMP-activated protein kinase (AMPK)...
Autores principales: | Hinchy, Elizabeth C., Gruszczyk, Anja V., Willows, Robin, Navaratnam, Naveenan, Hall, Andrew R., Bates, Georgina, Bright, Thomas P., Krieg, Thomas, Carling, David, Murphy, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222118/ https://www.ncbi.nlm.nih.gov/pubmed/30232152 http://dx.doi.org/10.1074/jbc.RA118.002579 |
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