Splicing Factor 3B Subunit 1 Interacts with HIV Tat and Plays a Role in Viral Transcription and Reactivation from Latency

The main obstacle to an HIV cure is the transcriptionally inert proviruses that persist in resting CD4 T cells and other reservoirs. None of the current approaches has significantly reduced the size of the viral reservoir. Hence, alternative approaches, such as permanent blocking of viral transcript...

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Detalles Bibliográficos
Autores principales: Kyei, George B., Meng, Shanshan, Ramani, Rashmi, Niu, Austin, Lagisetti, Chandraiah, Webb, Thomas R., Ratner, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222122/
https://www.ncbi.nlm.nih.gov/pubmed/30401776
http://dx.doi.org/10.1128/mBio.01423-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222122/
https://www.ncbi.nlm.nih.gov/pubmed/30401776
http://dx.doi.org/10.1128/mBio.01423-18

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