Leishmania Genome Dynamics during Environmental Adaptation Reveal Strain-Specific Differences in Gene Copy Number Variation, Karyotype Instability, and Telomeric Amplification

Protozoan parasites of the genus Leishmania adapt to environmental change through chromosome and gene copy number variations. Only little is known about external or intrinsic factors that govern Leishmania genomic adaptation. Here, by conducting longitudinal genome analyses of 10 new Leishmania clin...

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Detalles Bibliográficos
Autores principales: Bussotti, Giovanni, Gouzelou, Evi, Côrtes Boité, Mariana, Kherachi, Ihcen, Harrat, Zoubir, Eddaikra, Naouel, Mottram, Jeremy C., Antoniou, Maria, Christodoulou, Vasiliki, Bali, Aymen, Guerfali, Fatma Z., Laouini, Dhafer, Mukhtar, Maowia, Dumetz, Franck, Dujardin, Jean-Claude, Smirlis, Despina, Lechat, Pierre, Pescher, Pascale, El Hamouchi, Adil, Lemrani, Meryem, Chicharro, Carmen, Llanes-Acevedo, Ivonne Pamela, Botana, Laura, Cruz, Israel, Moreno, Javier, Jeddi, Fakhri, Aoun, Karim, Bouratbine, Aïda, Cupolillo, Elisa, Späth, Gerald F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222132/
https://www.ncbi.nlm.nih.gov/pubmed/30401775
http://dx.doi.org/10.1128/mBio.01399-18

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