Chlamydia trachomatis Inhibits Homologous Recombination Repair of DNA Breaks by Interfering with PP2A Signaling

Cervical and ovarian cancers exhibit characteristic mutational signatures that are reminiscent of mutational processes, including defective homologous recombination (HR) repair. How these mutational processes are initiated during carcinogenesis is largely unclear. Chlamydia trachomatis infections ar...

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Detalles Bibliográficos
Autores principales: Mi, Yang, Gurumurthy, Rajendra Kumar, Zadora, Piotr K., Meyer, Thomas F., Chumduri, Cindrilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222135/
https://www.ncbi.nlm.nih.gov/pubmed/30401777
http://dx.doi.org/10.1128/mBio.01465-18

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