Survival and glycemic control in patients with colorectal cancer and diabetes mellitus

AIM: The impact of diabetes mellitus (DM) on survival in patients with colorectal cancer and the impact of colorectal cancer on glycemic control were examined. MATERIALS & METHODS: Patients with colorectal cancer with and without DM were matched 1:1 (2007–2015). Characteristics were compared bet...

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Detalles Bibliográficos
Autores principales: Karlin, Nina J, Amin, Shailja B, Kosiorek, Heidi E, Buras, Matthew R, Verona, Patricia M, Cook, Curtiss B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222275/
https://www.ncbi.nlm.nih.gov/pubmed/30416744
http://dx.doi.org/10.4155/fsoa-2018-0044
Descripción
Sumario:AIM: The impact of diabetes mellitus (DM) on survival in patients with colorectal cancer and the impact of colorectal cancer on glycemic control were examined. MATERIALS & METHODS: Patients with colorectal cancer with and without DM were matched 1:1 (2007–2015). Characteristics were compared between the two groups and survival assessed with the Kaplan–Meier method. Mixed models compared hemoglobin A(1c) and glucose levels over time. RESULTS: In both groups, glucose values decreased during the year following cancer diagnosis (p < 0.001). 5-year overall survival was 56% (95% CI: 42–68%) for DM patients versus 57% (95% CI: 43–69%) for non-DM patients (p = 0.62). CONCLUSION: DM did not adversely impact survival of patients with colorectal cancer. Colorectal cancer did not affect glycemic control.

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