Cargando…

Safe Synthesis of 4,7-Dibromo[1,2,5]thiadiazolo[3,4-d]pyridazine and Its S(N)Ar Reactions

A safe and efficient synthesis of 4,7-dibromo[1,2,5]thiadiazolo[3,4-d]pyridazine from the commercial diaminomaleonitrile is reported. Conditions for selective aromatic nucleophilic substitution of one or two bromine atoms by oxygen and nitrogen nucleophiles are found, whereas thiols formed the bis-d...

Descripción completa

Detalles Bibliográficos
Autores principales: Chmovzh, Timofey N., Knyazeva, Ekaterina A., Lyssenko, Konstantin A., Popov, Vadim V., Rakitin, Oleg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222427/
https://www.ncbi.nlm.nih.gov/pubmed/30304797
http://dx.doi.org/10.3390/molecules23102576

Ejemplares similares