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Kinetic Resolution of Racemic 2-Hydroxyamides Using a Diphenylacetyl Component as an Acyl Source and a Chiral Acyl-Transfer Catalyst

Various optically active 2-hydroxyamide derivatives are produced based on the kinetic resolution of racemic 2-hydroxyamides with a diphenylacetyl component and (R)-benzotetramisole ((R)-BTM), a chiral acyl-transfer catalyst, via asymmetric esterification and acylation. It was revealed that a tertiar...

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Detalles Bibliográficos
Autores principales: Murata, Takatsugu, Kawanishi, Tatsuya, Sekiguchi, Akihiro, Ishikawa, Ryo, Ono, Keisuke, Nakata, Kenya, Shiina, Isamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222459/
https://www.ncbi.nlm.nih.gov/pubmed/30103468
http://dx.doi.org/10.3390/molecules23082003

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