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Neuroprotective Role of Phytochemicals
Neurodegenerative diseases are normally distinguished as disorders with loss of neurons. Various compounds are being tested to treat neurodegenerative diseases (NDs) but they possess solitary symptomatic advantages with numerous side effects. Accumulative studies have been conducted to validate the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222499/ https://www.ncbi.nlm.nih.gov/pubmed/30262792 http://dx.doi.org/10.3390/molecules23102485 |
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author | Velmurugan, Bharath Kumar Rathinasamy, Baskaran Lohanathan, Bharathi Priya Thiyagarajan, Varadharajan Weng, Ching-Feng |
author_facet | Velmurugan, Bharath Kumar Rathinasamy, Baskaran Lohanathan, Bharathi Priya Thiyagarajan, Varadharajan Weng, Ching-Feng |
author_sort | Velmurugan, Bharath Kumar |
collection | PubMed |
description | Neurodegenerative diseases are normally distinguished as disorders with loss of neurons. Various compounds are being tested to treat neurodegenerative diseases (NDs) but they possess solitary symptomatic advantages with numerous side effects. Accumulative studies have been conducted to validate the benefit of phytochemicals to treat neurodegenerative diseases including Alzheimer’s disease (AD) and Parkinson’s disease (PD). In this present review we explored the potential efficacy of phytochemicals such as epigallocatechin-3-galate, berberin, curcumin, resveratrol, quercetin and limonoids against the most common NDs, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). The beneficial potentials of these phytochemicals have been demonstrated by evidence-based but more extensive investigation needs to be conducted for reducing the progression of AD and PD. |
format | Online Article Text |
id | pubmed-6222499 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62224992018-11-13 Neuroprotective Role of Phytochemicals Velmurugan, Bharath Kumar Rathinasamy, Baskaran Lohanathan, Bharathi Priya Thiyagarajan, Varadharajan Weng, Ching-Feng Molecules Review Neurodegenerative diseases are normally distinguished as disorders with loss of neurons. Various compounds are being tested to treat neurodegenerative diseases (NDs) but they possess solitary symptomatic advantages with numerous side effects. Accumulative studies have been conducted to validate the benefit of phytochemicals to treat neurodegenerative diseases including Alzheimer’s disease (AD) and Parkinson’s disease (PD). In this present review we explored the potential efficacy of phytochemicals such as epigallocatechin-3-galate, berberin, curcumin, resveratrol, quercetin and limonoids against the most common NDs, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). The beneficial potentials of these phytochemicals have been demonstrated by evidence-based but more extensive investigation needs to be conducted for reducing the progression of AD and PD. MDPI 2018-09-27 /pmc/articles/PMC6222499/ /pubmed/30262792 http://dx.doi.org/10.3390/molecules23102485 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Velmurugan, Bharath Kumar Rathinasamy, Baskaran Lohanathan, Bharathi Priya Thiyagarajan, Varadharajan Weng, Ching-Feng Neuroprotective Role of Phytochemicals |
title | Neuroprotective Role of Phytochemicals |
title_full | Neuroprotective Role of Phytochemicals |
title_fullStr | Neuroprotective Role of Phytochemicals |
title_full_unstemmed | Neuroprotective Role of Phytochemicals |
title_short | Neuroprotective Role of Phytochemicals |
title_sort | neuroprotective role of phytochemicals |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222499/ https://www.ncbi.nlm.nih.gov/pubmed/30262792 http://dx.doi.org/10.3390/molecules23102485 |
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