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Neuroprotective Role of Phytochemicals

Neurodegenerative diseases are normally distinguished as disorders with loss of neurons. Various compounds are being tested to treat neurodegenerative diseases (NDs) but they possess solitary symptomatic advantages with numerous side effects. Accumulative studies have been conducted to validate the...

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Autores principales: Velmurugan, Bharath Kumar, Rathinasamy, Baskaran, Lohanathan, Bharathi Priya, Thiyagarajan, Varadharajan, Weng, Ching-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222499/
https://www.ncbi.nlm.nih.gov/pubmed/30262792
http://dx.doi.org/10.3390/molecules23102485
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author Velmurugan, Bharath Kumar
Rathinasamy, Baskaran
Lohanathan, Bharathi Priya
Thiyagarajan, Varadharajan
Weng, Ching-Feng
author_facet Velmurugan, Bharath Kumar
Rathinasamy, Baskaran
Lohanathan, Bharathi Priya
Thiyagarajan, Varadharajan
Weng, Ching-Feng
author_sort Velmurugan, Bharath Kumar
collection PubMed
description Neurodegenerative diseases are normally distinguished as disorders with loss of neurons. Various compounds are being tested to treat neurodegenerative diseases (NDs) but they possess solitary symptomatic advantages with numerous side effects. Accumulative studies have been conducted to validate the benefit of phytochemicals to treat neurodegenerative diseases including Alzheimer’s disease (AD) and Parkinson’s disease (PD). In this present review we explored the potential efficacy of phytochemicals such as epigallocatechin-3-galate, berberin, curcumin, resveratrol, quercetin and limonoids against the most common NDs, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). The beneficial potentials of these phytochemicals have been demonstrated by evidence-based but more extensive investigation needs to be conducted for reducing the progression of AD and PD.
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spelling pubmed-62224992018-11-13 Neuroprotective Role of Phytochemicals Velmurugan, Bharath Kumar Rathinasamy, Baskaran Lohanathan, Bharathi Priya Thiyagarajan, Varadharajan Weng, Ching-Feng Molecules Review Neurodegenerative diseases are normally distinguished as disorders with loss of neurons. Various compounds are being tested to treat neurodegenerative diseases (NDs) but they possess solitary symptomatic advantages with numerous side effects. Accumulative studies have been conducted to validate the benefit of phytochemicals to treat neurodegenerative diseases including Alzheimer’s disease (AD) and Parkinson’s disease (PD). In this present review we explored the potential efficacy of phytochemicals such as epigallocatechin-3-galate, berberin, curcumin, resveratrol, quercetin and limonoids against the most common NDs, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). The beneficial potentials of these phytochemicals have been demonstrated by evidence-based but more extensive investigation needs to be conducted for reducing the progression of AD and PD. MDPI 2018-09-27 /pmc/articles/PMC6222499/ /pubmed/30262792 http://dx.doi.org/10.3390/molecules23102485 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Velmurugan, Bharath Kumar
Rathinasamy, Baskaran
Lohanathan, Bharathi Priya
Thiyagarajan, Varadharajan
Weng, Ching-Feng
Neuroprotective Role of Phytochemicals
title Neuroprotective Role of Phytochemicals
title_full Neuroprotective Role of Phytochemicals
title_fullStr Neuroprotective Role of Phytochemicals
title_full_unstemmed Neuroprotective Role of Phytochemicals
title_short Neuroprotective Role of Phytochemicals
title_sort neuroprotective role of phytochemicals
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222499/
https://www.ncbi.nlm.nih.gov/pubmed/30262792
http://dx.doi.org/10.3390/molecules23102485
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