Density Functional Studies on Secondary Amides: Role of Steric Factors in Cis/Trans Isomerization

Cis/trans isomerization of amide bonds is a key step in a wide range of biological and synthetic processes. Occurring through C-N amide bond rotation, it also coincides with the activation of amides in enzymatic hydrolysis. In recently described QM studies of cis/trans isomerization in secondary ami...

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Detalles Bibliográficos
Autores principales: Thakkar, Balmukund S., Svendsen, John Sigurd M., Engh, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222500/
https://www.ncbi.nlm.nih.gov/pubmed/30257481
http://dx.doi.org/10.3390/molecules23102455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222500/
https://www.ncbi.nlm.nih.gov/pubmed/30257481
http://dx.doi.org/10.3390/molecules23102455

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